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Figure 4 | Nuclear Receptor

Figure 4

From: The peroxisome proliferator activated receptor δ is required for the differentiation of THP-1 monocytic cells by phorbol ester

Figure 4

Over-expression of PPARδ potentiates the differentiation response. A: Both wild type (squares) and SENSE cells (inverted triangles) were treated with increasing concentrations of PMA. Numbers of adherent cells were quantified by SYBR green staining and compared to a standard curve. B: Over-expression of PPARδ (inverted triangles) enhances the maintenance of adhesion following a single treatment with PMA when compared with the parental cell line (squares). For comparison, the compound F result (triangles; broken line) is also shown.

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