Skip to main content

Advertisement

Figure 2 | Nuclear Receptor

Figure 2

From: Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors)

Figure 2

Summary of PAML β-distribution ω ratio variation models. The plots are derived from the estimated β-distribution parameters for the M7 (or M8, if statistically superior to M7) models for the NR genes and show for a particular gene how many codons have estimated ω ratios equal to or less than a particular ω ratio on the abscissa. In contrast to Figure 1, only data derived from analyses of all available species are included in Figure 2 (i.e., mammals-only comparisons are not included). (A), (B), and (C) apply to analyses of full-length sequences, DBD only, and LBD only, respectively. For part (C), the red curve represents data for the LBD of the AHR gene. Analysis in part (A) is for NR1A1, 1B1, 1C1, 1F2, 1H3, 1I1, 1I2, 1I3, 2A1, 2B1, 3A1, 3A2, 3B1, 3C1, 3C3, 4A1, 5A1, 6A1, 0B1, and OB2; for part (B), analysis is for NR1A1, 1B1, 1C1, 1H3, 1I1, 1I2, 1I3, 2A1, 2B1, 3A1, 3A2, 3B1, 3C1, 3C3, 4A1, 5A1, and 6A1; and for part (C), analysis is for NR1A1, 1B1, 1F2, 1H3, 1I1, 1I2, 1I3, 2A1, 2B1, 3A1, 3A2, 3B1, 3C1, 3C3, 4A1, 5A1, 6A1, 0B1, OB2, and AHR.

Back to article page