From: SF-1 a key player in the development and differentiation of steroidogenic tissues
Gene promoter | Cell type /Transgenic technique | Basal activity/induction by cAMP | Bibliography |
---|---|---|---|
hP450scc | Additive transgenesis, H-295 | basal + induction | |
rP450scc | MA-10, rat granulosa | basal | |
bP450scc | Y1, bovine luteal cells, COS1 | basal + induction | [162] |
h3β-HSD type II | H295, HeLa | basal + N.D. | [189] |
mCYP21 | Y1 | basal + N.D. | |
hCYP11B1 | Y1, H295 | basal + induction | |
bCYP11B1 | Y1, I-10 (Leydig) | basal + induction. | |
hCYP17 | H295 | basal + induction | |
bCYP17 | Y1, COS-1 | basal + induction | |
rCYP19 | R2C, H450, Y1 | basal + induction | |
hCYP19 | Bovine luteal cells | basal + induction | [85] |
h/mCYP11B2 | H295 | inhibition by SF-1 | [78] |
AKR1-B7 | Additive transgenesis, HeLa, CV-1 | basal | |
HDL-R/SR-BI | Y1, HTB9 | basal + induction | |
SCP2 | Y1, HTB9 | basal + induction | [199] |
hStAR | Y1, BeWo, H295 | basal + induction | |
mStAR | Y1, MA-10 | basal | [112] |
rStAR | Y1, HTB9 (human bladder carcinoma) | basal + induction | [204] |
bStAR | HeLa | basal + induction | [205] |
HMG-CoA reductase | CV-1, MA-10 | basal + N.D. | [89] |
hMC2R | H295-R | basal + induction | |
mMC2R | Y1 | basal + N.D. | [208] |
mFSH-R | HEK-293 | basal | [60] |
rFSH-R | JEG-3 | basal + inhibition of PKA induction | [209] |
rLH-R | Granulosa | basal inhibition | [210] |
R-GNRH | αT3-1 | basal | |
LHβ | Additive transgenesis, LβT2, αT3-1, | basal + induction by GnRH in association with Sp1, EGR-1 and Ptx1 | |
hαGSU | LβT2 gonadotropes | basal + induction by GnRH | [215] |
Neuronal mNOS | αT3-1, NIH3T3 | basal | [96] |
b-ocytocin | TM4 | basal | |
PRL-R | MLTC (Leydig) | basal | [218] |
MIS | Knock-in mice, HeLa, JEG-3 | basal | |
DAX-1 | Additive transgenesis, H295, JEG-3 | basal | |
RLF/INSL3 | MA-10, HeLa, mLTC-1, HEK293 | basal | |
α-inhibin | tsa, GRMO2 granulosa | basal + induction | [163] |