Figure 6From: Stat3 enhances transactivation of steroid hormone receptorsActive Stat3 modifies the sensitivity of AR for androgen. CV-1 cells were cotransfected with ARE-TATA-luciferase, AR, and Stat3C (solid bars) or empty vector (empty bars), and treated for 36–40 h with different doses of R1881 or 0.1% ethanol as vehicle, in 5% charcoal stripped serum in phenol red-free DMEM. Luciferase activity was determined in cell extracts and corrected per μg of protein. Data are expressed as mean ± S.E. of three independent experiments.Back to article page