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Table 1 Expression of HNF4α protein and mRNA in human and rat tissues. Summary of HNF4α protein and mRNA expression levels in human and rat tissues.

From: Expression and localization of P1 promoter-driven hepatocyte nuclear factor-4α (HNF4α) isoforms in human and rats

 

Immunohistochemistry

mRNA expression

 

Rat

Human

RT-PCR

GeneChip

Brain

-

-

-

25.0

Epidermis

-

-

n.t.

21.9 (skin)

Kidney

+

+

+

413.9

   Glomeruli

-

-

  

   Proximal tubules

+

+

  

   Henle's loops

-

-

  

   Distal tubules

-

-

  

   Collecting ducts

-

-

  

Liver

+

+

+

467.6

   Hepatocytes

+

+

  

Pancreas

-

-

n.t.

20.0

Heart

-

-

-

14.1

White adipose tissue

-

-

n.t.

n.t.

Spleen

-

-

-

9.2

Esophagus

-

-

n.t.

n.t.

Stomach

-

-

n.t.

35.0

Small intestine

+

+

+

291.8

Colon

+

+

+

186.3

Bladder

-

-

n.t.

17.2

Testis

-

-

-

7.2

Ovary

-

-

n.t.

15.5

Adrenal gland

-

-

-

15.2

Uterus

-

-

-

11.5

Thymus

-

-

-

19.8

Thyroid gland

-

-

-

24.2

Trachea

-

-

-

20.1

Lung

-

-

-

12.1

Breast

n.t.

n.t.

n.t.

13.4

Salivary gland

-

n.t.

-

10.6

Skeletal muscle

-

-

-

9.2

Placenta

-

-

-

10.1

Prostate

n.t.

n.t.

-

6.5

  1. +, positive; -, undetectable; n.t., not tested. Data were taken from both results shown in Figs. 2, 3 and 5.
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Nuclear Receptor

ISSN: 1478-1336